BUY GHK-Cu 100mg

GHK-Cu, also known as copper tripeptide-1, is a naturally occurring copper-binding peptide complex formed from glycyl-L-histidyl-L-lysine (GHK) and copper ions. GHK was first identified in human plasma in the 1970s, and research has since examined its role in cellular signaling, extracellular matrix regulation, collagen and elastin biology, and tissue-remodeling pathways.

GHK has a high affinity for copper and forms the GHK-Cu complex under physiological conditions. Laboratory research has investigated GHK-Cu in models of fibroblast activity, extracellular matrix remodeling, angiogenic signaling, oxidative stress, and skin-cell biology. A 2015 review described its ability to influence collagen, glycosaminoglycan, metalloproteinase, and related cellular pathways, while later research has continued to examine its molecular effects.

Recent research continues to explore copper-peptide systems. A 2026 study investigated GHK-Cu incorporated into a hydrogel system and examined its interaction with glucose oxidation, oxygen generation, and tissue-repair processes in an experimental wound model.

For research purposes, GHK-Cu is therefore of interest in peptide chemistry, copper-binding biology, cellular signaling, extracellular matrix research, and skin-cell models. Much of the evidence remains preclinical, so further research is needed to characterize its mechanisms across different experimental systems.

Research Use Only: This product, and all products available at Sequora Peptides,  are intended exclusively for laboratory research. It is not intended for human or veterinary use, diagnosis, treatment, or prevention of disease.

Research Papers References

1. Pickart L, Vasquez-Soltero JM, Margolina A. (2015). GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration. BioMed Research International.
2. Pickart L, Margolina A. (2018). Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. International Journal of Molecular Sciences.
3. Aguilar L, et al. (2026). Copper(II)-Tripeptide Complexes as Potential Skin Healing Agents: Synthesis, Characterization, and Wound Repair Ability. ChemMedChem. DOI: 10.1002/cmdc.202501023.
4. Huang ZJ, et al. (2026). Copper Peptide Activated Cascade Catalysis for Glucose Regulation and Hypoxia Reversing in Infected Diabetic Wound Healing. Materials Today Bio. DOI: 10.1016/j.mtbio.2026.103396.